PRODUCTION OF A MONOCLONAL ANTIBODY TO THE NUCLEOCAPSID PROTEIN OF SARS-COV-2 AND ITS APPLICATION TO ELISA-BASED DETECTION METHODS WITH BROAD SPECIFICITY BY COMBINED USE OF DETECTOR ANTIBODIES

Production of a Monoclonal Antibody to the Nucleocapsid Protein of SARS-CoV-2 and Its Application to ELISA-Based Detection Methods with Broad Specificity by Combined Use of Detector Antibodies

The coronavirus disease 2019 pandemic, elicited by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is ongoing.Currently accessible antigen-detecting rapid diagnostic tests are limited by their low lsu tote bag sensitivity and detection efficacy due to evolution of SARS-CoV-2 variants.Here, we produced and characterized an anti-SARS-Co

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Species determination of Culicoides biting midges via peptide profiling using matrix-assisted laser desorption ionization mass spectrometry

Abstract Background Culicoides biting midges are vectors of bluetongue and Schmallenberg viruses that inflict large-scale disease epidemics in ruminant livestock in Europe.Methods based on morphological characteristics and sequencing of genetic markers are most commonly employed to differentiate Culicoides to species level.Proteomic methods, howeve

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